CHEMBL306377


SMILES c1ccc2c(c1)CCCC2NC1=NCCCO1
InChIKey LAMFPOWZDAOQTK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 230.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 7.6 7.6 7.6 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 7.07 7.07 7.07 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 5.66 5.69 5.71 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.59 7.59 7.59 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pEC50 7.46 7.46 7.46 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 7.61 7.61 7.61 ChEMBL
α2A ADA2A Human Adrenoceptors A pEC50 6.64 6.64 6.64 ChEMBL