CHEMBL306384


SMILES COc1ccc(C(=O)Nc2ccc(-c3ccc(-c4noc(C)n4)cc3C)cc2)cc1N1CCN(C)CC1
InChIKey BRWASLBCBODGKZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 497.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Guinea pig 5-Hydroxytryptamine A pKi 8.2 8.2 8.2 ChEMBL
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pKi 8.2 8.2 8.2 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 5.9 5.9 5.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database