CHEMBL3084515


SMILES O[C@]1(c2ccc(Cl)cc2)C[C@@H]2CC[C@H](C1)N2Cc1coc2ccccc12
InChIKey CNNRPXDUHKLPGW-NGRWLJPCSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 367.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.71 6.71 6.71 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.41 5.41 5.41 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.15 9.15 9.15 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.77 6.77 6.77 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.75 5.75 5.75 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.97 8.97 8.97 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pIC50 9.07 9.07 9.07 ChEMBL
D2 DRD2 Human Dopamine A pIC50 8.72 8.72 8.72 ChEMBL