CHEMBL3262091


SMILES CC[C@@](O)(c1ccccc1)[C@H]1C[C@@]23CC[C@]1(OC)[C@@H]1Oc4c(O)ccc5c4[C@@]12CCN(CC1CC1)[C@@H]3C5
InChIKey GFFDOSHSNIMJQO-JGSIVOCFSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 501.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 6.4 6.4 6.4 ChEMBL
δ OPRD Human Opioid A pKi 9.1 9.1 9.1 ChEMBL
κ OPRK Human Opioid A pKi 9.44 9.44 9.44 ChEMBL
μ OPRM Human Opioid A pKi 9.0 9.0 9.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 8.05 8.05 8.05 ChEMBL
κ OPRK Human Opioid A pEC50 6.6 6.6 6.6 ChEMBL
μ OPRM Human Opioid A pEC50 7.74 7.74 7.74 ChEMBL