CHEMBL3289648
SMILES | Cc1ccc(N2CCN(CCCCc3ccc(F)cc3)CC2)nc1 |
InChIKey | KERODJLVCVZLOA-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 0 |
Rotatable bonds | 6 |
Molecular weight (Da) | 327.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D4 | DRD4 | Rat | Dopamine | A | pKi | 7.64 | 7.64 | 7.64 | ChEMBL |
D5 | DRD5 | Human | Dopamine | A | pKi | 5.49 | 5.5 | 5.5 | ChEMBL |
5-HT7 | 5HT7R | Human | 5-Hydroxytryptamine | A | pKi | 7.2 | 7.21 | 7.22 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 7.64 | 7.64 | 7.64 | ChEMBL |
D1 | DRD1 | Human | Dopamine | A | pKi | 6.28 | 6.28 | 6.28 | ChEMBL |
5-HT2C | 5HT2C | Human | 5-Hydroxytryptamine | A | pKi | 5.79 | 5.79 | 5.79 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 6.8 | 6.8 | 6.81 | ChEMBL |
5-HT2A | 5HT2A | Human | 5-Hydroxytryptamine | A | pKi | 6.86 | 6.86 | 6.86 | ChEMBL |
5-HT1A | 5HT1A | Human | 5-Hydroxytryptamine | A | pKi | 7.03 | 7.04 | 7.04 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 5.7 | 5.71 | 5.73 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |