Ligand Data

Ligand

id 112356
Name CHEMBL3287695
SMILES COc1cc(C(=O)O)ccc1OCCCCOc1ccc(C(=O)CC(C)C)c(O)c1C
InChIKey XJICBRVIAXTUNH-UHFFFAOYSA-N
Type small-molecule
External Links

Structure

Properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 12
Molecular weight 430.2


Bioactivity

Receptor Affinity (nM) Potency (nM)
GTP Uniprot Species Family Class Min Avg Max Min Avg Max
mGlu3 GRM3 Rat Metabotropic glutamate C (Glutamate) 614 1192 1771
mGlu2 GRM2 Rat Metabotropic glutamate C (Glutamate) 12.0 66.7 148.0