Ligand Data
Ligand
| Name | CHEMBL3287695 |
| SMILES | COc1cc(C(=O)O)ccc1OCCCCOc1ccc(C(=O)CC(C)C)c(O)c1C |
| InChIKey | XJICBRVIAXTUNH-UHFFFAOYSA-N |
| Type | small-molecule |
| External Links |
Structure
Properties
| Hydrogen bond acceptors | 6 |
| Hydrogen bond donors | 2 |
| Rotatable bonds | 12 |
| Molecular weight | 430.2 |
Bioactivity
| Receptor | Affinity (nM) | Potency (nM) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Min | Avg | Max | Min | Avg | Max |
| mGlu3 | GRM3 | Rat | Metabotropic glutamate | C (Glutamate) | 614 | 1192 | 1771 | |||
| mGlu2 | GRM2 | Rat | Metabotropic glutamate | C (Glutamate) | 12.0 | 66.7 | 148.0 | |||