CHEMBL3318832


SMILES O=C(CCCC(=O)OC1(c2ccc(Cl)cc2)CCN(CCCC(=O)c2ccc(F)cc2)CC1)OC1(c2ccc(Cl)cc2)CCN(CCCC(=O)c2ccc(F)cc2)CC1
InChIKey ZNZYEIAZHCDSRA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 0
Rotatable bonds 18
Molecular weight (Da) 846.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 6.66 6.66 6.66 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.48 7.48 7.48 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.51 7.51 7.51 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.92 7.92 7.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database