Chembl335542

Chemical Properties

SMILES CN1CCC=C(c2nsnc2OCCOCCOCCOCCOc2nsnc2C2=CCCN(C)C2)C1
Hydrogen bond acceptors 13
Hydrogen bond donors 0
Rotatable bonds 16
Molecular weight 552.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey NHUURXLCGOCXHZ-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 7.2 7.2 7.2 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pEC50 8.28 8.28 8.28 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.7 8.7 8.7 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 8.3 8.3 8.3 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 9.9 9.9 9.9 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pIC50 9.2 9.2 9.2 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 7.0 9.23 10.0 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pEC50 6.54 7.68 8.1 ChEMBL