secretin


SMILES None
InChIKey KKNIUBFRGPFELP-UHFFFAOYSA-N
Sequence HSDGTFTSELSRLRDSARLQRLLQGLV

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Endogenous/Surrogate Endogenous
Approved drug Yes

Database connections

Ligand site mutations PTH1 secretin

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 9.5 9.5 9.5 Guide to Pharmacology
D4 DRD4 Human Dopamine A pKi 8.47 8.47 8.47 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.3 6.3 6.3 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.75 6.75 6.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Mouse 5-Hydroxytryptamine A pIC50 6.75 6.75 6.75 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 6.82 6.82 6.82 ChEMBL