GnRH I


SMILES None
InChIKey NMJREATYWWNIKX-UHFFFAOYSA-N
Sequence XHWSYGLRPG

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Endogenous/Surrogate Endogenous
Approved drug No

Database connections


Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GnRH1 GNRHR Human Gonadotrophin-releasing hormone A pKi 7.3 8.0 8.4 Guide to Pharmacology
GnRH1 GNRHR Human Gonadotrophin-releasing hormone A pKd 7.66 8.1 8.54 Guide to Pharmacology
GnRH1 GNRHR Rat Gonadotrophin-releasing hormone A pKi 6.8 6.8 6.8 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GnRH1 GNRHR Human Gonadotrophin-releasing hormone A pEC50 10.0 10.0 10.0 Guide to Pharmacology
GnRH1 GNRHR Human Gonadotrophin-releasing hormone A pIC50 8.6 8.6 8.6 Guide to Pharmacology
GnRH1 GNRHR Rat Gonadotrophin-releasing hormone A pIC50 7.7 7.7 7.7 Guide to Pharmacology
GnRH1 GNRHR Mouse Gonadotrophin-releasing hormone A pIC50 8.3 8.3 8.3 Guide to Pharmacology
GnRH1 GNRHR Mouse Gonadotrophin-releasing hormone A pEC50 7.77 7.85 7.92 Guide to Pharmacology