Chembl338687

Chemical Properties

SMILES CCCCC(=O)Nc1ccc(Br)c(-n2nc(CC)n(Cc3ccc(-c4ccccc4S(=O)(=O)NC(=O)OC(C)C)cc3F)c2=O)c1
Hydrogen bond acceptors 9
Hydrogen bond donors 2
Rotatable bonds 12
Molecular weight 715.1

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey FVWOWORFCQFYEN-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
AT2 AGTR2 Rat Angiotensin A pIC50 9.74 9.87 10.0 ChEMBL
AT1 AGTR1 Rabbit Angiotensin A pIC50 9.09 9.09 9.09 ChEMBL
AT1 AGTR1 Human Angiotensin A pIC50 8.37 8.37 8.37 ChEMBL
AT2 AGTR2 Human Angiotensin A pIC50 8.96 8.96 8.96 ChEMBL