CHEMBL1182182


SMILES COc1ccc2ccccc2c1OCCNC[C@H]1COc2ccccc2O1
InChIKey MRCKSWXOWOMYII-KRWDZBQOSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 365.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2A ADA2A Rat Adrenoceptors A pKd 5.87 5.87 5.87 ChEMBL
α1D ADA1D Rat Adrenoceptors A pKd 10.68 10.68 10.68 ChEMBL
α1B ADA1B Rat Adrenoceptors A pKd 9.69 9.69 9.69 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 7.8 7.8 7.8 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKd 8.96 8.96 8.96 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 8.8 8.8 8.8 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 8.18 8.18 8.18 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.95 7.95 7.95 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database