CHEMBL3260336


SMILES FC(F)(COc1ccc(Cl)cc1OC1CNC1)c1ccccc1
InChIKey GJKAUYNNNVUARP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 339.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.64 7.64 7.64 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.92 7.92 7.92 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.42 7.42 7.42 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.3 8.3 8.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database