CP55940
SMILES | CCCCCCC(c1ccc(c(c1)O)[C@@H]1C[C@H](O)CC[C@H]1CCCO)(C)C |
InChIKey | YNZFFALZMRAPHQ-SYYKKAFVSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 3 |
Rotatable bonds | 10 |
Molecular weight (Da) | 376.3 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
CB1 | CNR1 | Human | Cannabinoid | A | pKi | 8.3 | 8.75 | 9.2 | Guide to Pharmacology |
CB1 | CNR1 | Human | Cannabinoid | A | pKd | 8.5 | 8.95 | 9.4 | Guide to Pharmacology |
CB2 | CNR2 | Human | Cannabinoid | A | pKi | 8.6 | 8.9 | 9.2 | Guide to Pharmacology |
CB2 | CNR2 | Human | Cannabinoid | A | pKd | 8.1 | 8.9 | 9.7 | Guide to Pharmacology |
CB1 | CNR1 | Mouse | Cannabinoid | A | pKi | 8.82 | 9.02 | 9.21 | ChEMBL |
CB1 | CNR1 | Rat | Cannabinoid | A | pKi | 8.11 | 8.8 | 9.24 | ChEMBL |
CB2 | CNR2 | Human | Cannabinoid | A | pKi | 7.47 | 8.83 | 9.82 | ChEMBL |
CB2 | CNR2 | Human | Cannabinoid | A | pKd | 9.23 | 9.23 | 9.23 | ChEMBL |
CB1 | CNR1 | Human | Cannabinoid | A | pKi | 7.89 | 8.9 | 9.57 | ChEMBL |
CB1 | CNR1 | Human | Cannabinoid | A | pKd | 9.3 | 9.3 | 9.3 | ChEMBL |
CB2 | CNR2 | Mouse | Cannabinoid | A | pKi | 8.96 | 8.96 | 8.96 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
GPR55 | GPR55 | Human | GPR18, GPR55 and GPR119 | A | pEC50 | 8.3 | 8.3 | 8.3 | Guide to Pharmacology |
CB2 | CNR2 | Rat | Cannabinoid | A | pEC50 | 9.47 | 9.47 | 9.47 | ChEMBL |
CB1 | CNR1 | Mouse | Cannabinoid | A | pEC50 | 7.38 | 7.38 | 7.38 | ChEMBL |
GPR55 | GPR55 | Human | GPR18, GPR55 and GPR119 | A | pEC50 | 5.79 | 5.79 | 5.79 | ChEMBL |
CB1 | CNR1 | Rat | Cannabinoid | A | pEC50 | 7.0 | 8.06 | 9.8 | ChEMBL |
CB1 | CNR1 | Rat | Cannabinoid | A | pIC50 | 8.4 | 8.4 | 8.4 | ChEMBL |
CB2 | CNR2 | Human | Cannabinoid | A | pEC50 | 6.25 | 8.15 | 9.46 | ChEMBL |
CB2 | CNR2 | Human | Cannabinoid | A | pIC50 | 8.08 | 8.79 | 9.09 | ChEMBL |
CB1 | CNR1 | Human | Cannabinoid | A | pIC50 | 7.56 | 8.87 | 9.89 | ChEMBL |
CB1 | CNR1 | Human | Cannabinoid | A | pEC50 | 6.8 | 8.31 | 9.59 | ChEMBL |
NPS | NPSR1 | Human | Neuropeptide S | A | Potency | 4.9 | 4.9 | 4.9 | ChEMBL |
TSH | TSHR | Human | Glycoprotein hormone | A | Potency | 5.2 | 5.2 | 5.2 | ChEMBL |
GPR18 | GPR18 | Human | GPR18, GPR55 and GPR119 | A | pIC50 | 5.22 | 5.22 | 5.22 | ChEMBL |
GPR18 | GPR18 | Human | GPR18, GPR55 and GPR119 | A | pEC50 | 5.22 | 5.22 | 5.22 | ChEMBL |