CHEMBL105267


SMILES N#Cc1ccc(-c2ccc(OCCCN3CC[C@@H](N)C3)cc2)cc1
InChIKey RRBSCZCNYAJFEJ-LJQANCHMSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 321.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 7.2 7.2 7.2 ChEMBL
H2 HRH2 Human Histamine A pKi 5.13 5.13 5.13 ChEMBL
H3 HRH3 Human Histamine A pKi 8.21 8.21 8.21 ChEMBL
H1 HRH1 Human Histamine A pKi 4.86 4.86 4.86 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database