T-98475


SMILES CC(OC(=O)c1cn(Cc2c(F)cccc2F)c2c(c1=O)c(CN(Cc1ccccc1)C)c(s2)c1ccc(cc1)NC(=O)C(C)C)C
InChIKey RANJJVIMTOIWIN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 11
Molecular weight (Da) 657.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
glucagon GLR Human Glucagon B1 pKd 9.79 9.88 9.96 Guide to Pharmacology
glucagon GLR Rat Glucagon B1 pKd 10.82 10.82 10.82 Guide to Pharmacology
glucagon GLR Mouse Glucagon B1 pKd 10.05 10.29 10.52 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database