2-(3-iodophenyl)histamine


SMILES NCCc1cnc([nH]1)c1cccc(c1)I
InChIKey OPICWPJAKDPOOB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 313.0

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PAF PTAFR Human Platelet-activating factor A pKi 6.16 6.2 6.24 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PAF PTAFR Human Platelet-activating factor A pIC50 6.8 6.8 6.8 Guide to Pharmacology
PAF PTAFR Guinea pig Platelet-activating factor A pIC50 4.59 4.85 5.11 ChEMBL
PAF PTAFR Human Platelet-activating factor A pIC50 6.22 6.22 6.22 ChEMBL