CHEMBL352925


SMILES c1ccc(C2=NCC[C@H](CN3CCN(c4ccccc4)CC3)N2)cc1
InChIKey BJWYIHWMKMZYRS-LJQANCHMSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 334.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 4.54 4.54 4.54 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.82 8.82 8.82 ChEMBL
D3 DRD3 Human Dopamine A pKi 4.89 4.89 4.89 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.5 4.55 4.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 7.3 7.3 7.3 ChEMBL