GPCRdb

UCSF924

Agent/drug
Bioactivity

UCSF924

SMILES	Cc1ccc2nc(CNCCCOc3ccccc3)cc(O)c2c1
InChIKey	RPHDOVLXDYWDGF-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	2
Rotatable bonds	7
Molecular weight (Da)	322.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

α_1A	ADA1A	Human	Adrenoceptors	A	pKi	5.00	5.00	5.00	ChEMBL
α_1B	ADA1B	Human	Adrenoceptors	A	pKi	5.00	5.00	5.00	ChEMBL
α_2A	ADA2A	Human	Adrenoceptors	A	pKi	5.00	5.00	5.00	ChEMBL
α_2B	ADA2B	Human	Adrenoceptors	A	pKi	5.52	5.55	5.59	ChEMBL
α_2C	ADA2C	Human	Adrenoceptors	A	pKi	5.00	5.00	5.00	ChEMBL
β₁	ADRB1	Human	Adrenoceptors	A	pKi	5.00	5.00	5.00	ChEMBL
β₂	ADRB2	Human	Adrenoceptors	A	pKi	5.00	5.00	5.00	ChEMBL
δ	OPRD	Human	Opioid	A	pKi	5.00	5.00	5.00	ChEMBL
κ	OPRK	Human	Opioid	A	pKi	5.64	5.65	5.66	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	5.00	5.00	5.00	ChEMBL
5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	6.65	6.66	6.67	ChEMBL
5-HT_1B	5HT1B	Human	5-Hydroxytryptamine	A	pKi	5.47	5.47	5.48	ChEMBL
5-HT_1D	5HT1D	Human	5-Hydroxytryptamine	A	pKi	5.49	5.50	5.50	ChEMBL
5-HT_1E	5HT1E	Human	5-Hydroxytryptamine	A	pKi	5.00	5.00	5.00	ChEMBL
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	5.49	5.50	5.50	ChEMBL
5-HT_2B	5HT2B	Human	5-Hydroxytryptamine	A	pKi	6.63	6.64	6.65	ChEMBL
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pKi	5.26	5.26	5.26	ChEMBL
5-HT₄	5HT4R	Human	5-Hydroxytryptamine	A	pKi	5.17	5.19	5.20	ChEMBL
5-HT_5A	5HT5A	Human	5-Hydroxytryptamine	A	pKi	5.24	5.25	5.25	ChEMBL
5-HT₆	5HT6R	Human	5-Hydroxytryptamine	A	pKi	5.17	5.19	5.20	ChEMBL

Showing 1 to 20 of 33 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₄	DRD4	Human	Dopamine	A	pEC50	8.38	8.71	9.70	ChEMBL

Showing 1 to 1 of 1 entry

UCSF924

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.