Chembl3589154
Chemical Properties
| SMILES | COc1cc(-n2cnc3cc(-c4ccc(Cl)cc4)sc3c2=O)ccc1OCC(C)(C)O |
| Hydrogen bond acceptors | 7 |
| Hydrogen bond donors | 1 |
| Rotatable bonds | 6 |
| Molecular weight | 456.1 |
Drug Properties
| Type | Small molecule |
| Endogenous | No |
| Approved | No |
| InChIKey | GRPZZKMUWKOODM-UHFFFAOYSA-N |
Bioactivity
| Receptor | Experimental Data | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| MCH1 | MCHR1 | Rat | Melanin-concentrating hormone | A | pKi | 8.14 | 8.14 | 8.14 | ChEMBL |
| MCH1 | MCHR1 | Human | Melanin-concentrating hormone | A | pIC50 | 7.8 | 7.84 | 7.89 | ChEMBL |