4-methylhistamine
| SMILES | Cc1c(CCN)nc[nH]1 |
| InChIKey | UGYXPZQILZRKJJ-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 2 |
| Hydrogen bond donors | 2 |
| Rotatable bonds | 2 |
| Molecular weight (Da) | 125.1 |
Drug properties
| Molecular type | Small molecule |
| Endogenous/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| H4 | HRH4 | Human | Histamine | A | pKi | 7.3 | 7.75 | 8.2 | Guide to Pharmacology |
| H2 | HRH2 | Human | Histamine | A | pKi | 5.1 | 5.1 | 5.1 | ChEMBL |
| H3 | HRH3 | Human | Histamine | A | pKi | 5.2 | 5.2 | 5.2 | ChEMBL |
| H4 | HRH4 | Human | Histamine | A | pKi | 7.3 | 7.3 | 7.3 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| H1 | HRH1 | Human | Histamine | A | pEC50 | 4.8 | 4.8 | 4.8 | ChEMBL |
| H2 | HRH2 | Human | Histamine | A | pEC50 | 5.5 | 5.52 | 5.54 | ChEMBL |
| H3 | HRH3 | Human | Histamine | A | pEC50 | 4.91 | 4.91 | 4.91 | ChEMBL |
| H4 | HRH4 | Human | Histamine | A | pEC50 | 7.15 | 7.35 | 7.5 | ChEMBL |
| H4 | HRH4 | Mouse | Histamine | A | pEC50 | 5.8 | 5.8 | 5.8 | ChEMBL |
| H4 | HRH4 | Rat | Histamine | A | pEC50 | 5.6 | 5.6 | 5.6 | ChEMBL |