CHEMBL3335538


SMILES FC(F)(F)Oc1ccc(CN2CCOC(CCc3ccccc3)C2)cc1
InChIKey RXEIDFSWABFHSZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 365.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.37 7.37 7.37 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.56 5.56 5.56 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.26 5.26 5.26 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pIC50 6.8 6.8 6.8 ChEMBL
D3 DRD3 Human Dopamine A pIC50 5.09 5.09 5.09 ChEMBL