CHEMBL3590077


SMILES COc1ccccc1N1CCN(CCCCNC(=O)/N=N/c2ccc(F)cc2)CC1
InChIKey HLWTUGVLYCATKY-OCEACIFDSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 413.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 5.55 5.55 5.55 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.89 5.89 5.89 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.03 7.03 7.03 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.27 6.27 6.27 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.51 8.52 8.52 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.42 7.45 7.47 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database