CHEMBL3586414


SMILES COc1ccc(C(=O)N2C[C@H]3CN(c4nc5ccc(Cl)cc5s4)C[C@H]3C2)c(OC)c1
InChIKey HVCAOBUVVPALEM-OKILXGFUSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 443.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 5.28 5.28 5.28 ChEMBL
OX2 OX2R Human Orexin A pKi 6.29 6.29 6.29 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database