CHEMBL3597595


SMILES Cc1cccc(C#CC=C2CCN(c3ccccc3)CC2)n1
InChIKey PGDZTLDIKMARHN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 1
Molecular weight (Da) 288.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 7.04 7.04 7.04 ChEMBL
mGlu5 GRM5 Human Metabotropic glutamate C pKi 7.54 7.54 7.54 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Human Metabotropic glutamate C pIC50 7.26 7.26 7.26 ChEMBL