Chembl3622329
Chemical Properties
| SMILES | C[C@@H]1CCN(c2ncc(C(F)(F)F)c(Cl)n2)CCN1C(=O)c1ccccc1-n1nccn1 |
| Hydrogen bond acceptors | 7 |
| Hydrogen bond donors | 0 |
| Rotatable bonds | 3 |
| Molecular weight | 465.1 |
Drug Properties
| Type | Small molecule |
| Endogenous | No |
| Approved | No |
| InChIKey | CZFJNTVOOOARTK-CYBMUJFWSA-N |
Bioactivity
| Receptor | Experimental Data | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| OX2 | OX2R | Human | Orexin | A | pIC50 | 7.0 | 7.0 | 7.0 | ChEMBL |
| OX2 | OX2R | Human | Orexin | A | pKi | 8.29 | 8.29 | 8.29 | ChEMBL |