Chembl3622329

Chemical Properties

SMILES C[C@@H]1CCN(c2ncc(C(F)(F)F)c(Cl)n2)CCN1C(=O)c1ccccc1-n1nccn1
Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight 465.1

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey CZFJNTVOOOARTK-CYBMUJFWSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX2 OX2R Human Orexin A pIC50 7.0 7.0 7.0 ChEMBL
OX2 OX2R Human Orexin A pKi 8.29 8.29 8.29 ChEMBL