CHEMBL1185884


SMILES COc1ccc2ccccc2c1OCCNC[C@@H]1COc2ccccc2O1
InChIKey MRCKSWXOWOMYII-QGZVFWFLSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 365.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2A ADA2A Rat Adrenoceptors A pKd 6.2 6.2 6.2 ChEMBL
α1D ADA1D Rat Adrenoceptors A pKd 8.0 8.0 8.0 ChEMBL
α1B ADA1B Rat Adrenoceptors A pKd 7.83 7.83 7.83 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 7.07 7.07 7.07 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKd 7.23 7.23 7.23 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 8.34 8.34 8.34 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.65 7.65 7.65 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.17 7.17 7.17 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database