Chembl3634395

Chemical Properties

SMILES COC(=O)N1CCN(C(=O)Cc2ccc(Cl)c(Cl)c2)[C@@H]2[C@@H]1CCC[C@H]2N1CCCC1
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight 453.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey PAVYSOUZQLFNIW-DYXWJJEUSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Rat Opioid A pKi 6.28 6.28 6.28 ChEMBL
κ OPRK Guinea pig Opioid A pKi 7.71 7.71 7.71 ChEMBL
κ OPRK Human Opioid A pEC50 6.9 6.9 6.9 ChEMBL