Chembl3634396

Chemical Properties

SMILES COC(=O)N1CCN(C(=O)Cc2ccc(Cl)c(Cl)c2)[C@H]2[C@@H](N3CCCC3)CCC[C@H]21
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight 453.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey PAVYSOUZQLFNIW-ZVDOUQERSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 7.24 7.24 7.24 ChEMBL
κ OPRK Human Opioid A pKi 5.92 5.92 5.92 ChEMBL
κ OPRK Human Opioid A pEC50 6.46 6.46 6.46 ChEMBL