CHEMBL3634010


SMILES COc1cccc(C(C)NC(=O)COc2cc(C(F)(F)F)c3c(-c4ccccc4)nn(C)c3n2)c1
InChIKey XICVVFDXUOCBKP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 484.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 7.7 7.7 7.7 ChEMBL
OX1 OX1R Human Orexin A pKd 7.38 7.38 7.38 ChEMBL
OX2 OX2R Human Orexin A pKi 7.58 7.58 7.58 ChEMBL
OX2 OX2R Human Orexin A pKd 7.0 7.0 7.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database