CHEMBL3403340


SMILES COc1cccc(-n2cc(C(=O)N(C)c3cccc(Cl)c3)c3ccccc3c2=O)c1
InChIKey XQDBHEUHZJUZOG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 418.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 4.57 4.57 4.57 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 4.78 4.78 4.78 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 4.54 4.54 4.54 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 4.9 4.9 4.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database