impentamine
| SMILES | NCCCCCc1cnc[nH]1 |
| InChIKey | MZCJWLAXZRFUPI-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 2 |
| Hydrogen bond donors | 2 |
| Rotatable bonds | 5 |
| Molecular weight (Da) | 153.1 |
Drug properties
| Molecular type | Small molecule |
| Endogenous/Surrogate | Surrogate |
| Approved drug | No |
Database connections
| Ligand site mutations | H3 |
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| α1A | ADA1A | Human | Adrenoceptors | A | pKi | 7.9 | 7.9 | 7.9 | Guide to Pharmacology |
| α1D | ADA1D | Human | Adrenoceptors | A | pKi | 8.5 | 8.5 | 8.5 | Guide to Pharmacology |
| α1D | ADA1D | Rat | Adrenoceptors | A | pKi | 7.6 | 7.6 | 7.6 | Guide to Pharmacology |
| α1D | ADA1D | Rat | Adrenoceptors | A | pKd | 7.27 | 7.83 | 9.21 | ChEMBL |
| α1D | ADA1D | Rat | Adrenoceptors | A | pKi | 9.24 | 9.24 | 9.24 | ChEMBL |
| α1B | ADA1B | Rat | Adrenoceptors | A | pKd | 9.16 | 9.17 | 9.18 | ChEMBL |
| α1B | ADA1B | Human | Adrenoceptors | A | pKi | 9.16 | 9.6 | 9.87 | ChEMBL |
| α1A | ADA1A | Human | Adrenoceptors | A | pKi | 7.6 | 7.92 | 8.26 | ChEMBL |
| α1D | ADA1D | Human | Adrenoceptors | A | pKi | 7.5 | 8.56 | 9.77 | ChEMBL |
| D2 | DRD2 | Rat | Dopamine | A | pKi | 5.08 | 5.08 | 5.08 | ChEMBL |
| 5-HT1A | 5HT1A | Rat | 5-Hydroxytryptamine | A | pKi | 5.21 | 5.21 | 5.21 | ChEMBL |
| α1B | ADA1B | Human | Adrenoceptors | A | pKi | 9.9 | 9.9 | 9.9 | Guide to Pharmacology |
| α1A | ADA1A | Rat | Adrenoceptors | A | pKd | 7.48 | 7.98 | 8.91 | ChEMBL |
| α1A | ADA1A | Rat | Adrenoceptors | A | pKi | 8.77 | 8.77 | 8.77 | ChEMBL |
| α1A | ADA1A | Bovine | Adrenoceptors | A | pKi | 8.62 | 8.62 | 8.62 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |