CHEMBL3423340


SMILES Cc1cn2c3c(=O)n(C)c(=O)n(C)c3nc2n1CCCCCN1CCN(c2ccc(Cl)c(Cl)c2)CC1
InChIKey QAJBLBPQVIYECG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 9
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 531.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.96 6.96 6.96 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.66 7.66 7.66 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.39 6.39 6.39 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.23 7.23 7.23 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database