ICI-89406


SMILES C1=CC=C(C=C1)NC(=O)NCCNCC(COC2=CC=CC=C2C#N)O
InChIKey HTLWRKRZKFAAAH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 9
Molecular weight (Da) 354.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 6.72 6.72 6.72 ChEMBL
κ OPRK Human Opioid A pKi 9.06 9.06 9.06 ChEMBL
μ OPRM Human Opioid A pKi 8.57 8.57 8.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database