CHEMBL3663464


SMILES CCOc1nccc(Br)c1C(=O)N1C2CCC1C(COc1ccccn1)C2
InChIKey VOJZFYPEPNWTDP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 431.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Rat Orexin A pKi 6.32 6.32 6.32 ChEMBL
OX2 OX2R Human Orexin A pKi 5.84 5.84 5.84 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database