CHEMBL3665713


SMILES COc1ccc(C(C)NC(=O)COc2cc(C(F)F)c3c(-c4ccccc4)nn(C)c3n2)cn1
InChIKey XUCPLVDEFHBGNJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 467.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 7.25 7.25 7.25 ChEMBL
OX2 OX2R Human Orexin A pKd 7.38 7.38 7.38 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database