CHEMBL3665726


SMILES COc1ccc2c(c1)CC[C@@H]2NC(=O)COc1cc(C(F)(F)F)c2c(C3CC3)nn(C)c2n1
InChIKey ZGUXBVWYPWYBCZ-KRWDZBQOSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 460.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 6.69 6.69 6.69 ChEMBL
OX2 OX2R Human Orexin A pKd 7.75 7.75 7.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database