CHEMBL3669536


SMILES N=C(CN1CCCC2(CCN(c3cnc4ccccc4n3)CC2)C1=O)c1ccccc1N
InChIKey ZLOPZXCPZADDAN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 428.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 6.9 6.9 6.9 ChEMBL
OX1 OX1R Human Orexin A pKd 6.98 6.98 6.98 ChEMBL
OX2 OX2R Human Orexin A pKi 8.05 8.05 8.05 ChEMBL
OX2 OX2R Human Orexin A pKd 7.6 7.6 7.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database