CHEMBL3669463


SMILES Cc1onc(-c2ccccc2)c1CN1CCCC2(CCN(c3cnc4ccccc4n3)CC2)C1=O
InChIKey WUXPKZJKAXKBRE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 467.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 5.37 5.37 5.37 ChEMBL
OX1 OX1R Human Orexin A pKi 5.81 5.81 5.81 ChEMBL
OX2 OX2R Human Orexin A pKd 6.74 6.74 6.74 ChEMBL
OX2 OX2R Human Orexin A pKi 7.06 7.06 7.06 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database