CHEMBL361061


SMILES CN1CCC(N2CCc3ccc(NC(=O)c4ccc(F)cc4)cc32)CC1
InChIKey RKMQUAXCYSFRJS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 353.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pKi 8.32 8.32 8.32 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.36 6.36 6.36 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.68 6.68 6.68 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.92 7.92 7.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database