CHEMBL3616851


SMILES Nc1nnc(S[C@@H]2C[C@@](N)(C(=O)O)[C@@H]3[C@@H](C(=O)O)[C@H]23)[nH]1
InChIKey PZICKINIOPPAGP-UESLGPDASA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 5
Rotatable bonds 4
Molecular weight (Da) 299.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pKi 7.23 7.23 7.23 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKi 7.17 7.17 7.17 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pIC50 7.02 7.02 7.02 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pEC50 7.13 7.13 7.13 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 7.89 8.12 8.35 ChEMBL