CHEMBL3616854


SMILES N[C@@]1(C(=O)O)C[C@H](Sc2nnc[nH]2)[C@H]2[C@H](C(=O)O)[C@H]21
InChIKey YSOWRGMLMZQSBX-LWEFNAMFSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 4
Molecular weight (Da) 284.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pKi 6.9 6.9 6.9 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pKi 7.22 7.22 7.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu3 GRM3 Human Metabotropic glutamate C pIC50 5.37 5.44 5.51 ChEMBL
mGlu3 GRM3 Human Metabotropic glutamate C pEC50 6.64 6.64 6.64 ChEMBL
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 7.16 7.55 7.95 ChEMBL