TPI 1361-17
SMILES | Fc1cccc(c1)CCN1[C@@H](CCCN=C(N)N)CN(C1=S)[C@H](CNCc1ccccc1)C |
InChIKey | DSJVYEAOYVHUJW-CVDCTZTESA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 3 |
Rotatable bonds | 12 |
Molecular weight (Da) | 470.3 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
MCH1 | MCHR1 | Human | Melanin-concentrating hormone | A | pIC50 | 8.2 | 8.2 | 8.2 | Guide to Pharmacology |
MCH1 | MCHR1 | Rat | Melanin-concentrating hormone | A | pIC50 | 8.21 | 8.21 | 8.21 | ChEMBL |