afamelanotide


SMILES None
InChIKey UAHFGYDRQSXQEB-LEBBXHLNSA-N
Sequence SYSXEHFRWGKPV

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Endogenous/Surrogate Surrogate
Approved drug Yes

Database connections

Structure pdb 7F54 7PIV
Ligand site mutations MC4

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NPS NPSR1 Mouse Neuropeptide S A pA2 6.4 6.4 6.4 Guide to Pharmacology
NPS NPSR1 Rat Neuropeptide S A pA2 6.6 6.6 6.6 Guide to Pharmacology
NPS NPSR1 Mouse Neuropeptide S A pEC50 7.86 7.86 7.86 ChEMBL