CHEMBL3697996


SMILES O=C(N[C@H]1CC[C@H](CCN2CCN(c3cccc4c3OCO4)CC2)CC1)c1ccc(F)cc1
InChIKey ZTNICFPCCSHZEL-XYWHTSSQSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 453.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 8.42 8.42 8.42 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.54 7.54 7.54 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.08 7.08 7.08 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database