S24014


SMILES COc1cccc(c1)Cc1oc2c(c1CCNC(=O)C)cc(cc2)OC
InChIKey GNWDMICUDNQPEK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 353.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
B1 BKRB1 Human Bradykinin A pKi 5.7 5.75 5.8 Guide to Pharmacology
B1 BKRB1 Mouse Bradykinin A pKi 9.2 9.2 9.2 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
B2 BKRB2 Human Bradykinin A pIC50 5.1 5.1 5.1 Guide to Pharmacology
B2 BKRB2 Mouse Bradykinin A pIC50 5.2 5.2 5.2 Guide to Pharmacology