CHEMBL3669481


SMILES O=C1N(Cc2ccnc(-n3cccn3)c2)CCCC12CCN(c1cnc3ccccc3n1)CC2
InChIKey JTBPCXHLACNRFP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 453.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 6.05 6.05 6.05 ChEMBL
OX1 OX1R Human Orexin A pKd 5.42 5.42 5.42 ChEMBL
OX2 OX2R Human Orexin A pKd 6.04 6.04 6.04 ChEMBL
OX2 OX2R Human Orexin A pKi 7.08 7.08 7.08 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database