CHEMBL3669521


SMILES O=C1N(Cc2cccc3nsnc23)CCCC12CCN(c1cnc3ccccc3n1)CC2
InChIKey QVYPQEYTLBZOID-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 444.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 5.87 5.87 5.87 ChEMBL
OX1 OX1R Human Orexin A pKd 5.46 5.46 5.46 ChEMBL
OX2 OX2R Human Orexin A pKi 7.09 7.09 7.09 ChEMBL
OX2 OX2R Human Orexin A pKd 6.2 6.2 6.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database