CHEMBL373707


SMILES C[C@H]1CN2C[C@H](c3ccccc3)NC[C@H]2C[C@@]1(C)c1cccc(C(N)=O)c1
InChIKey NVFASTTYRDVPEF-JNHGLSHCSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 363.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 7.22 7.22 7.22 ChEMBL
κ OPRK Human Opioid A pKi 7.96 7.96 7.96 ChEMBL
μ OPRM Human Opioid A pKi 8.74 8.74 8.74 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pIC50 6.96 6.96 6.96 ChEMBL
κ OPRK Human Opioid A pIC50 8.64 8.64 8.64 ChEMBL
μ OPRM Human Opioid A pIC50 8.82 8.82 8.82 ChEMBL