CHEMBL3765873


SMILES COc1ccccc1N1CCN(CCCCC(=O)n2c3ccccc3c3ccccc32)CC1
InChIKey CKSKIWUQLNHIJX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 441.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 8.3 8.3 8.3 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 5.43 5.43 5.43 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.33 6.33 6.33 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.52 7.52 7.52 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.03 7.03 7.03 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.93 5.93 5.93 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.91 6.91 6.91 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.35 6.35 6.35 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database